Diseases have caused the most destructive impact and become a primary constraint to shrimp aquaculture, impeding economic development in many countries including Thailand. An example of the negative impact of infectious diseases in shrimp farming is the unprecedented economic loss caused by outbreaks of the emerging disease called early mortality syndrome (EMS) or officially named of Acute Hepatopancreatic Necrosis Disease (AHPND) which consequently impacted the shrimp industry as evidenced by 40-50% reduction in the production of farmed shrimps.
One of the effective strategies to control disease outbreaks is selection for disease resistant animals. Previously, a successful selection for shrimp resistance to Taura syndrome virus has provided remarkable economic benefits to the industry. However, different shrimp breeding lines which resist to other pathogens especially Vibrio parahaemolyticus causing strain of AHPND and white spot syndrome virus (WSSV) should be further developed. Furthermore, the knowledge on mechanisms of disease resistance in shrimp remains largely unknown and needs to be further elucidated.
Genomic selection is a powerful approach which incorporate molecular information to increase the accuracy of genetic selection for the disease resistance traits. In this study, we propose to use genomic information available through International Genomics Network to address the issues of disease resistance in shrimp with the aims to gain more knowledge on the mechanisms of disease resistance and apply to assist selective breeding of shrimp lines resistance to AHPND and WSSV by developing genomics tools such as a platform of gene expression profile, allele specific markers to screen for the desired shrimp traits. Our International Genomics Research Network on Disease Resistance in Shrimp will strengthen the research capability through collaboration among Thai, Taiwanese and Belgian researchers with the ultimate goal to establish an effective genomics process for breeding selection for disease resistance shrimp. The outcome of this research will lead to a sustainable development of shrimp aquaculture.
- To develop and utilize genome information resources available through the Genomics Network for identification of genetic loci (SNPs)/genes associated with disease resistance traits
- To develop effective genomic processes to assist in breeding for enhanced resistance to AHPND- and WSSV in shrimp Penaeus monodon and Litopenaeus vannamei
- To elucidate mechanisms involved in disease resistance in Penaeid shrimp